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Naltrexone

I will start with naltrexone, which can help people who have difficulty regulating their drinking have a more natural and sustainable relationship with alcohol should they choose to not cut it out of their lives entirely.

  • Newtra
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    37 months ago

    Since it’s a natural hormone the body already has ways to get rid of it. It has a half-life of less than an hour. The lethal dose is so high we haven’t been able to intentionally kill animals with it: “Melatonin is not fatal even at a dose of 800 mg/kg in animal studies”.

    The big risk of ongoing high doses is becoming so dependent on it that you wake up as soon as it wears off (e.g. after only 4 hours of sleep). At this level you basically can’t sleep without it and have to slowly wean yourself off to get back to normality.

    • @cheese_greater@lemmy.worldOP
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      fedilink
      17 months ago

      I found my dreams were extremely vivid and often extra-disturbing when my dose was high to the extent Im implying. Also, because it was so vivid and palpable, I just didnt feel rested cuz I was so engaged/engrossed by it