A lot of drugs cause permanent problems when abused, and are still prescribed. Testing is needed to figure out if there’s safe dosing and whatnot. Worse, safe dosage for one person may be incredibly unsafe for another, just like with depression meds which can permanently cause mental issues (in addition to depression) at normally prescribed and “safe” dosages. This is why honest discussions and ongoing check ins with your doctor is vital in any prescription change. Hell, penicillin almost killed my mom, and that’s relatively safe unless you have an allergic reaction.

Definitely hard to test with drugs that offer non medical and very obvious side effects. Hopefully there is an interesting breakthrough in understanding mechanics so we can make safe PTSD helping meds, but something so drastically painful to the person having it may not have a safe cure because the systems that go haywire are so ingrained in the preservation systems of our brains.

Brains are weird. Any tampering is possibly dangerous.