• Glasgow@lemmy.ml
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    8 days ago

    The cases are on average more extreme now though.

    My dad’s full side is ADHD/ASD. But the millennials/genZs have more severe cases than their uncles and great uncles did.

    You can look at all the related disorders that are often comorbid like autoimmune, thyroid, MCAS, etc.

    Look at conditions like Type1 diabetes which is growing ~3% per year! This isn’t just better diagnostics but explained by the stress diathesis model of disease interacting with our modern synthetic world.

    • protist@mander.xyz
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      8 days ago

      The cases are on average more extreme now though

      This is based on your personal experience and not the evidence, which does not bear that out

        • protist@mander.xyz
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          7 days ago

          That article doesn’t say what you seem to think it says. It only talks about an increase in diagnosed cases, which can be explained away by more frequent assessments, better awareness of symptoms, the loosening of diagnostic criteria in the DSM IV, and over-diagnosis to get children with other severe developmental disorders qualified for services. There are lots of reasons we know about that autism is being diagnosed more frequently, but the best you’re going to get on your hypothesis is “we don’t know.”

          https://www.scientificamerican.com/article/the-real-reasons-autism-rates-are-up-in-the-u-s/

          Experts say the bulk of the increase stems from a growing awareness of autism and changes to the condition’s diagnostic criteria.

          https://www.annualreviews.org/content/journals/10.1146/annurev.publhealth.28.021406.144007

          Environmental risk factors may also play a role, perhaps via complex gene-environment interactions, but no specific exposures with significant population effects are known

          https://www.autismspeaks.org/autism-statistics-asd

          Autism prevalence is lower among white children than other racial and ethnic groups:

          White – 2.4%, Black – 2.9%, Hispanic – 3.2%, Asian or Pacific Islander – 3.3%

          These changes reflect an improvement in outreach, screening and de-stigmatization of autism diagnosis among minority communities.

          • Glasgow@lemmy.ml
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            11 hours ago

            It only talks about an increase in diagnosed cases

            Yes, in the type of autism least likely to be missed previously.

            which can be explained away by more frequent assessments, better awareness of symptoms, the loosening of diagnostic criteria in the DSM IV, and over-diagnosis to get children with other severe developmental disorders qualified for services. There are lots of reasons we know about that autism is being diagnosed more frequently, but the best you’re going to get on your hypothesis is “we don’t know.”

            Sure, but there’s no evidence it isn’t also increasing, and plenty of evidence it is.

            Environmental risk factors may also play a role, perhaps via complex gene-environment interactions, but no specific exposures with significant population effects are known

            This downplays the importance of environmental factors. It’s not just a “may also” situation.

            • Twin studies: Identical twins have a higher concordance rate for autism than fraternal twins, suggesting a strong genetic component. However, the concordance rate isn’t 100%, meaning environmental factors must be involved.
            • Increasing prevalence: The rising rates of autism diagnoses cannot be solely explained by genetics. Changes in diagnostic criteria play a role, but environmental factors likely contribute to this trend.
            • Specific environmental links: While no single factor has a massive population-level effect, research has identified several environmental factors associated with increased autism risk such as advanced parental age, valproic acid, air pollution and other prenatal exposures. All of which have increased over time. Hence, the rate of autism is increasing, not just our diagnostic ability.

            A more accurate statement:

            “Environmental factors play a crucial role in the development of autism, often through complex interactions with genetic predispositions. While no single environmental exposure universally causes autism, research has identified several factors that significantly increase risk, including advanced parental age, prenatal exposures to certain medications and infections, and birth complications. Ongoing research continues to uncover the intricate interplay between genes and environment in autism.”

            https://www.autismspeaks.org/autism-statistics-asd

            Autism Speaks is a hate org and should not be referenced.

            Now, do you think it’s a coincendence so many trans people are autists? Or maybe there is a biological explanation?

            Studies have suggested a higher prevalence of non-heterosexual orientations and gender nonconformity in individuals with NCAH, particularly in females. This may be due to the impact of elevated androgens on brain development during critical periods. Mild mutations in CYP21A2 are relatively common, occurring in an estimated 20-30% of the general population. These mutations can lead to subtle variations in hormone levels, even in individuals without a formal NCAH diagnosis. These variations likely contribute to a spectrum of androgen-related traits, including those related to sexual development and behavior.

            If it were due to this gene cluster. You would expect to see the disorders it cause cluster in LGBT people (Auotimmune (SLE, RA, MS, T1D, Thyroid), Hypermobility, Schizophrenia/Autism/ADHD, CFS, MCAS, POTS).

            And for people to start noticing with threads like this;

            https://old.reddit.com/r/DrWillPowers/comments/wybnef/the_nonad_of_trans_i_continue_to_see_more/

    • Sas [she/her]@beehaw.org
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      8 days ago

      People also get a lot better at masking as they get older so younger people’s autism appears more severe than older people’s. Same is probably true for ADHD