I’ve been using a community profile that I’ve grown to really enjoy while playing the Space Exploration mod on my Steamdeck. Having a set of menu hotkeys mapped to the trackpads virtual buttons is very convenient. It is also setup to swap to a mini number pad when holding X. It is called “Factorio Steam Deck by Zirbs” if anyone is curious and wants to check it out. Works with vanilla but is designed with SE in mind.

I’ll need to test out the official version again to see how it fairs - I only briefly used it while checking out the switch demo back when it first came out. With the new button support it may be possible to make an even better layout.