I feel like I am at a point in my transition where I might benefit from adding progesterone into the equation. However, I have heard wildly different opinions on whether it has any impact at all, and criticism of generally available creams on amazon for not being the same as human progesterone, since they are often derived from plants.

What do you girls think? Are they junk, or are there some out there worth trying?

  • Lumelore (She/her)@lemmy.blahaj.zone
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    10 months ago

    I honestly wouldn’t trust hormones from Amazon in any form, but I have heard that creams in general have a lower absorption rate.

    If you’re not doing DIY, it’d be best to talk to your doctor about it, since they’ll know the best form and dose of it for you to take and you’d also be able to get it from a pharmacy then too.

    One of my worries about hormones that aren’t from a pharmacy are that since there unfortunately are people out there who don’t like us, they may purposely make products to harm us (which has happened before, I don’t remember the name of that product though) or they may make products that don’t work to scam people who are desperate and trying to DIY.

    • Krrygon@lemmy.blahaj.zoneOP
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      10 months ago

      This is true. I remember one product called Femboy Tummy Pills that was just poison. I just had my HRT checkup, and I forgot to ask about prog so I am impatient lol. Might be best just to wait, thanks!

      • Lumelore (She/her)@lemmy.blahaj.zone
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        10 months ago

        Yeah, those femboy tummy pills were exactly what I was thinking of. If the clinic you go to has an online chart, you may be able to send them a message inquiring about prog, but you could also wait too if you feel that’s best.

  • LadyAutumn@lemmy.blahaj.zoneM
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    10 months ago

    I’d definitely be skeptical of Amazon products. I take prog in pill form and have had great results. I’ve never heard of it in cream form, honestly.

    • Krrygon@lemmy.blahaj.zoneOP
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      10 months ago

      Gotcha gotcha. Did you have an easy time getting a prescription for it? I have heard some health workers are hesitant to prescribe it because of the lack of clinical studies regarding it

      • LadyAutumn@lemmy.blahaj.zoneM
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        10 months ago

        Yeah, I had some pushback, but I mentioned it a few times and accepted any possible risks. I think it’s going to depend a lot on your doctor but I mentioned breast growth, hip size, and sex drive as motivating factors for taking it. I’ve been on it for around 4 years now.

          • LadyAutumn@lemmy.blahaj.zoneM
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            10 months ago

            I take tablets. I had already been on HRT for around 4 years when I first mentioned it to my doctor. My doctor is young and pretty progressive, even in a progressive area, but she showed a lot of hesitancy towards changing my medications. She was also misinformed and concerned about cancer risks.

            I will probably take it forever, yeah. I am post op and have unmeasurable T levels, so the prog keeps my energy and libido heightened and stable. I don’t cycle it and never have either, I just take it at night with half my daily E and half my daily Spiro.

              • LadyAutumn@lemmy.blahaj.zoneM
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                10 months ago

                Of course, happy to share my experience ❤️

                My doctor actually gatekept me from referring me for bottom surgery for 6 years. Having had it now I realize I should have gotten it many years ago, but my family doctor kept telling me that I wasn’t ready yet. I think in some way she thought she was trying to protect me, but those were some very long, very hard years of waiting. I live in a very progressive community with many laws that advocate for me but gatekeeping is still a very prevalent very real problem here.

  • Emily (she/her)@lemmy.blahaj.zone
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    10 months ago

    I’ve never heard of progesterone cream, but I definitely wouldn’t trust any from Amazon. I take oral progesterone and am very happy with the results

  • dandelion@lemmy.blahaj.zone
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    10 months ago

    I would take bio-identical progesterone (P4) prescribed by a doctor. The common recommendation is to press the pill (normally taken orally) up into the rectum, since taking it orally causes the liver to filter most of it. Bypassing the liver by putting it up the rectum allows it to absorb readily in the lower intestines.

    See:

    https://transfemscience.org/articles/transfem-intro/#rectal-progesterone

    A common recommendation is to start progesterone a year or two into HRT once the breasts have reached Tanner stage III, as taking it too early supposedly can negatively impact breast development (take this with a grain of salt, may or may not be true; there is also no empirical evidence progesterone helps breast development, it’s all anecdotal reports).

  • BassaForte@lemmy.world
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    10 months ago

    No, but I’ve heard that the best way to get progesterone is via suppository. Oral and creams allegedly aren’t as effective.